Novel Immuno-Oncology Target Screening Assay

  • Biochemical and cell-based screening assays for novel immunotherapy. 
  • IC50 determination for small or large molecules against immune targets for:  
    • PD-1:PD-L1/2,   PD-L1:B7-1, CTLA4:B7-1,  CTLA4:B7-2, BTLA:HVEM, CD28:B7-1, CD40: CD40L, CD47:Sirpα, CD137:CD137L, OX40:OX40L, GITR:GITRL, TIGIT: CD155,  VISTA, , TLRs, cGAS/STING, A2A receptor, CCR2/4/5 receptors, COX1/COX2, IDO/TDO,  HPK1 (Hematopoietic progenitor kinase 1) , SLP76, etc.
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