- A fully automated ultrasensitive immunoassay or digital ELISA based upon the isolation of individual immunocomplexes on paramagnetic beads using standard ELISA reagents.
- The main difference between SIMOA and traditional immunoassays lies in the ability to trap single molecules in femtoliter-sized wells, allowing for a "digital" readout of each bead to determine whether or not it is bound to the target analyte.
- Ability to detect and quantify low-abundance biomarkers difficult or impossible to measure with other conventional assays.
- Quantification of protein level as low as 1 fg/mL in the samples. The digital nature of the SIMOA technology allows an average 1000X sensitivity increase over conventional ELISA assays with CVs <10%.
